Dialysis is an artificial way of filtering the blood. It is a necessary treatment for patients diagnosed with end-stage renal disease (ESRD). In ESRD, kidney function has decreased to 70 - 751 of its original functioning which life is threatening without treatment. And dialysis patient may be faced with serious stressors related to the illness and its treatment, They are often confronted with limitations in food and fluid intake; with physical symptoms such as itching and lack of energy; with psychological stressors such as loss of self-concept and self-esteem, feelings of uncertainty about the future, and feelings of guilt towards family members; and with problems in the social domain. Aim of the study: Is to evaluate the effect of an educational program on quality of life for patient undergoing hemodialysis .Methods: A quasi experimental design was used for 00 patients undergoing haemodialysis in Dialysis Unit at Benha University Hospital Tools for data collection. Three tools were used in this study:7-Patient Interviewing questionnaire II-Patients knowledge assessment sheet to assess patient level of knowledge III- Kidney disease and quality of life short form questionnaire (KDQOL-SF 60 items): Developed for health educational program Results revealed that (10.11) of patient at 00