Objectives: Evaluation of the role of speckle tracking echocardiography in predicting left ventricular remodeling after anterior ST elevation myocardial infarction (STEMI) and successful primary percutaneous coronary intervention (PCI). Methods: A total of 100 first anterior STEMI and successful primary PCI were evaluated and divided into two groups according to the occurrence of left ventricular (LV) remodeling; remodeling group (n=26) and non remodeling group (n=74). Conventional and speckle tracking echocardiography were performed within 3 days of admission and 3 months later. Results: Twenty-six (26%) patients had LV remodeling at 3-month follow-up. They had comparable baseline clinical and echocardiographic characteristics with the non remodeling group except for β-blockers use (P =0.043), lower LV global longitudinal (LVGLS) and circumferential (LVGCS) strain (P