أعضاء هيئة التدريس - جامعة بنها
Serum levels of 25(OH) vitamin D and immunoglobulin E in infants with bronchiolitis
• 2017
معلومات البحث
المؤلفون
Bahaa El Din Mohamed Hassanein a, Doaa Refaey Soliman a,
Sahar Mohamed Abd Elhameed Fayed b, Mohamed Mosaad Mohamed Suleiman a,*
الكلمات المفتاحية
Not Available
المجلة العلمية
Not Available
الناشر
Not Available
المجلد
Not Available
العدد
Not Available
الصفحات
Not Available
publication.type
International
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
of this study: The aim of this study was to estimate and find the relationship between both
25(OH) vitamin D and immunoglobulin E serum levels and bronchiolitis in infancy.
Methods: We quantified serum 25(OH) D and serum immunoglobulin E using (ELISA) in 50
infants with bronchiolitis and 31 healthy controls of matched age and sex.
Results: The mean serum 25(OH) vitamin D was significantly lower in cases than in controls; it was
(12.3 ±3.9 & 26.2 ±10.0 ng/ml, respectively with p=0.003). The mean serum IgE was significantly
higher in cases than in controls; It was (170 ±66 & 43.8 ±14.2 IU/ml, respectively and
p= 0.01). Serum IgE showed a non-significant negative correlation with serum 25(OH) vitamin
D (r= 0.141, p= >0.05).
Conclusions: Serum 25(OH) vitamin D was found in decreased quantities in infants with bronchiolitis
and it was negatively correlated with serum IgE, suggesting that vitamin D may play a role in
the pathogenesis of bronchiolitis.
2016 The Egyptian Pediatric Association. Production and hosting by Elsevier B.V. This is an open access
article under the CC BY-NC-ND license
25(OH) vitamin D and immunoglobulin E serum levels and bronchiolitis in infancy.
Methods: We quantified serum 25(OH) D and serum immunoglobulin E using (ELISA) in 50
infants with bronchiolitis and 31 healthy controls of matched age and sex.
Results: The mean serum 25(OH) vitamin D was significantly lower in cases than in controls; it was
(12.3 ±3.9 & 26.2 ±10.0 ng/ml, respectively with p=0.003). The mean serum IgE was significantly
higher in cases than in controls; It was (170 ±66 & 43.8 ±14.2 IU/ml, respectively and
p= 0.01). Serum IgE showed a non-significant negative correlation with serum 25(OH) vitamin
D (r= 0.141, p= >0.05).
Conclusions: Serum 25(OH) vitamin D was found in decreased quantities in infants with bronchiolitis
and it was negatively correlated with serum IgE, suggesting that vitamin D may play a role in
the pathogenesis of bronchiolitis.
2016 The Egyptian Pediatric Association. Production and hosting by Elsevier B.V. This is an open access
article under the CC BY-NC-ND license