أعضاء هيئة التدريس - جامعة بنها
α-Substitution Effects on the Ease of S→N-Acyl Transfer in Aminothioesters
• 2013
معلومات البحث
المؤلفون
Bahaa El-Dien M. El-Gendy, Ebrahim H. Ghazvini Zadeh, Ania C. Sotuyo, Girinath G. Pillai andAlan R. Katritzky
الكلمات المفتاحية
Not Available
المجلة العلمية
Not Available
الناشر
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المجلد
Not Available
العدد
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الصفحات
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publication.type
International
رابط البحث
Open Link
المواد المرفقة
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الملخص
In S-acylcysteines and homocysteines, the efficacy and rate of S→N-acyl transfer (5 and 6 cyclic TSs) vary with the size of S-acyl group. Conformational and quantum chemical calculations indicate that the spatial distance, b(N-C), between the terminal amine and the thioester carbon is shortened by α-C(O)X (X = OH, OMe, NH2) substituents.