أعضاء هيئة التدريس - جامعة بنها
Comparative Study of the Efficacy of Combined Sofosbuvir Ribavirin in Treatment Naive versus Treatment Experienced Egyptian Patients with Chronic Hepatitis C
International Journal of Advanced Research • 2016
معلومات البحث
المؤلفون
Ayman El-Badawy1, Mohamed YehiaSeddek1, Mohamed Shawky El-sayed1 and Azez Mohammed
Bedeer2.
الكلمات المفتاحية
Not Available
المجلة العلمية
International Journal of Advanced Research
الناشر
Not Available
المجلد
4
العدد
11
الصفحات
1081-1087
publication.type
International
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
We conducted this study to assess the efficacy
of the oral nucleotide polymerase inhibitor sofosbuvir in combination
with ribavirin in Egyptian patients chronically infected with genotype
4 hepatitis C virus (HCV).
Methods: Treatment-naive and previously treated patients
withgenotype 4 HCV were randomly allocated in a 1:1 ratio to receive
sofosbuvir 400 mg and weight-based ribavirin , for 24 weeks. The
primary efficacy endpoint was the proportion of patients with
sustained virologic response (HCV RNA
of the oral nucleotide polymerase inhibitor sofosbuvir in combination
with ribavirin in Egyptian patients chronically infected with genotype
4 hepatitis C virus (HCV).
Methods: Treatment-naive and previously treated patients
withgenotype 4 HCV were randomly allocated in a 1:1 ratio to receive
sofosbuvir 400 mg and weight-based ribavirin , for 24 weeks. The
primary efficacy endpoint was the proportion of patients with
sustained virologic response (HCV RNA