أعضاء هيئة التدريس - جامعة بنها
Stereochemical aspects of novel 5,6-dihydro-4H-1,3-oxazines
J. Chem. Soc., Perkin Trans. • 2001
معلومات البحث
المؤلفون
Alan R. Katritzky,a Ion Ghiviriga,b Ke Chen,a Dmytro O. Tymoshenko a and
Ashraf A. A. Abdel-Fattah a
الكلمات المفتاحية
Not Available
المجلة العلمية
J. Chem. Soc., Perkin Trans.
الناشر
The Royal Society of Chemistry
المجلد
2
العدد
Not Available
الصفحات
530–537
publication.type
International
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Novel polysubstituted 5,6-dihydro-4H-1,3-oxazines are synthesized by 1,4-cycloaddition of unactivated olefins
with N-acyliminiums from benzotriazole precursors. The configuration and conformation of the products are
deduced from NMR investigation. The regio- and exo–endo stereochemistry of the cycloaddition are discussed.
Conformations of compounds of six types of substitution (6-mono; 6,6-, 5,6- and 4,6-di; 4,6,6- and 4,5,6-tri)
are rationalized on the basis of axial-1,3-repulsion and the anomeric effect.
with N-acyliminiums from benzotriazole precursors. The configuration and conformation of the products are
deduced from NMR investigation. The regio- and exo–endo stereochemistry of the cycloaddition are discussed.
Conformations of compounds of six types of substitution (6-mono; 6,6-, 5,6- and 4,6-di; 4,6,6- and 4,5,6-tri)
are rationalized on the basis of axial-1,3-repulsion and the anomeric effect.