A Two –year study was carried out at Ismailia Experimental Research Station, Agricultural Research Center (ARC), Ismailia Governorate, Egypt, during 2016/2017 and 2017/2018 seasons. This is to investigate the impact of different rates of NPK fertilizer and splitting on quinoa (Chenopoduim quinoa Willd.) yield and its
components. Twelve treatments were the combination of three rates of NPK fertilizer (100:75:100), (150:100:150)
and (200:150:200) kg/fed. They were applied in four splitting doses as follows: two equal doses (at 25 and 50 days after sowing [DAS]), three equal doses at 25, 40 and 52 DAS, four equal doses at 25, 40, 52 and 64 DAS, five equal doses at 25, 40, 52, 64 and 76 DAS. in sandy soil, under sprinkler irrigation system. A split plot
design, with three replications, was used. Results indicated that the growth of quinoa plants progressively increased with increasing NPK fertilizer. In addition, the superiority of the number of branches per plant, grain yield per plant, grain yield/fed, straw yield and biological yield were achieved when NPK was applied at
(150:113:150) rate and splitting in four doses. The maximum plant height was observed at the highest NPK rate in the combination (200:150:200) kg/fed and splitting in four doses. Grain content of N, P, K and protein were higher in the NPK fertilizer rate(150:113:150), recording (1.66, 0.98, 2.16 and 10.39 %), respectively regardless of the number of doses applied .Meanwhile, splitting the rate to four doses application recorded (1.75, 1.14, 2.24 and 10.96), respectively. It can be recommended that applying NPK fertilizer at the rate of (150:113:150) in four equal doses after 25, 40, 52 and 64 DAS, gave the best result of quality and quantity of quinoa (Chenopoduim quinoa Willd.) plants in sandy soil.