أعضاء هيئة التدريس - جامعة بنها
ENDOTHELIAL NITRIC OXIDE SYNTHASE 4A/B POLYMORPHISM AND ITS INTERACTION WITH G894T VARIANTS IN TYPE 2 DIABETES MELLITUS : PREDICTING THE RISK OF DIABETIC NEPHROPATHY
• 2016
معلومات البحث
المؤلفون
Azza Abo Senna, 1Jehan H Sabry, 1Mohamed A Al Hindi, 1Hesham A Eissa, 2Abdelmonem Ahmed, and Basma M Salem.
الكلمات المفتاحية
eNOS polymorphism,
Type 2 DM,
Diabetic nephropathy.
المجلة العلمية
Not Available
الناشر
Not Available
المجلد
Not Available
العدد
Not Available
الصفحات
Not Available
publication.type
International
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Background:
nitric oxide synthase (eNOS) and it regulates endothelial function. The presence of
might further complicate endothelial dysfunction and nephropathy through reduced production of NO.
This study
polymorphisms on the risk of diabetic nephr
Patients and Methods:
healthy subjects serving as a control group. All candidates were genotyped
polymorphism using PCR
Results
control for eNOS G894T and (4a/b) Polymorphisms
differences
with p value
and macroalbuminuria when compared with controls but the presence of
effect.
Conclusion:
4a or 894T allele, the risk of developing DN increased significantly. However, the presence of both
alleles together was
nitric oxide synthase (eNOS) and it regulates endothelial function. The presence of
might further complicate endothelial dysfunction and nephropathy through reduced production of NO.
This study
polymorphisms on the risk of diabetic nephr
Patients and Methods:
healthy subjects serving as a control group. All candidates were genotyped
polymorphism using PCR
Results
control for eNOS G894T and (4a/b) Polymorphisms
differences
with p value
and macroalbuminuria when compared with controls but the presence of
effect.
Conclusion:
4a or 894T allele, the risk of developing DN increased significantly. However, the presence of both
alleles together was