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Comparative Study Of Drug Coated Balloon Versus Bare-Metal Stenting In Management Of Femoro-popliteal Atherosclerotic Lesions

• 2017
العودة
معلومات البحث
المؤلفون Haitham Salama Afify
الكلمات المفتاحية Drug Coated Balloon, Bare-Metal Stenting, Femoro-popliteal Atherosclerosis, Outcomes.
المجلة العلمية Not Available
الناشر Not Available
المجلد Not Available
العدد Not Available
الصفحات Not Available
publication.type International
رابط البحث Not Available
المواد المرفقة Not Available
الملخص
Background: Despite enhanced immediate technical success, neointimal hyperplasia, stent fracture, and restenosis remain the Achilles heel of endovascular interventions. Aim: To emphasize results of bare metal stenting versus drug eluting balloon in superficial femoral artery occlusive lesions in critical limb ischemia as regard risk factors, tomography of stenotic lesion, associated co-morbidities, patency, success rates, total lesion revascularization and complications .Methods: This prospective randomized controlled study was conducted on 60 patients (81 limbs) complaining of lower limb symptomatic femoro-popliteal atherosclerotic lesions with Age over 40 years; Patients were randomly allocated by using a computer generated random number table into two groups according to the intervention method performed; Group (A); 30 patients (42 limbs) were submitted for treatment with paclitaxel Drug Coated Balloons (DCB) and Group (B); 30 patients (39 limbs) submitted for treatment with Bare Metal Stents (BMS). Follow-up period was for 12-monthes. Results: The Bare Metal Stents (BMS) had lower patency and limb salvage rates compared to patients who received Paclitaxel Drug Coated Balloons (DCB).The primary patency rates were 97.4%, 89.5%, 81.6%at 1, 6, 12 months respectively in group (A) Vs 97.4%, 78.9%, 77.8% at 1, 6, 12 months respectively in group (B), there was no 30 days mortality in both groups except 2 patient mortality in group (A) due to cardiac problems and the patients didn't need any re-intervention procedures in the 1st month except one limb (2.6%) in group (A); but Clinically TLR rates were 10.5%, 18.4% at 6, 12 months respectively in group (A) Vs 15.9%, 22.2% at 6, 12 months respectively in group (B). there was one major amputation (2.6%) in group (B) due to spreading infection despite presence of pedal pulse. Conclusion: Paclitaxel Drug Coated Balloons (DCB) seems to have a promising very important role in prevention of restenosis and recurrence of peripheral arterial occlusive disease. however; the stents still playing important bailout role in the treatment of peripheral arterial occlusive disease.