This paper proposes a cryptography technique based on two
dimension 2D chaotic system and DNA sequence. The 2D
chaotic map generates two artificial DNA sequences S1and S2
to get a cipher message by encrypting the plain message using
the first sequence S1. The sender uses the second sequence S2
to hide the cipher message randomly in a real third sequence
S3 that is selected from DNA database. The hamming code
approach is applied on the original message M to ensure
reliable secret communication. The proposed approach
provided a more security method compared to previous
approaches.